Peptide Database

Peptide NameDefensin alpha 7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC435H709N123O147S8

DescriptionStandard

        MRTLTLLTTLLLLLHTQAESPQGSRSTEEALDQEQLVMEDQDISISFGGDKGTALQDADVKSGVTCYCRLLSCQFGERLAGSCRSGGVTYPLCCH
    

Molecular Weight10270.54 Da

Isoelectric Point (pI)4.74

Net Charge (pH 7.0)-5.37

Net Charge (pH 7.4) -5.79

Charge Density (pH 7.0) -0.0565

GRAVY Index-0.10

Hydrophobic Moment 0.56

Boman Index0.02

Instability Index52.64

Aliphatic Index 87.26

Aromaticity 0.0421

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4353.87

LogP -52.60

H-bond Donors 158.0

H-bond Acceptors 152.0

Rotatable Bonds 346.0

Heavy Atoms 713.0

Ring Count 8.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023383 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence