Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC461H751N131O138S8

DescriptionStandard

        MRLLLLTFTVLVFLPQVTPAYGGRKRCWNNSGRCKKKCAADEVIRAVCKNRQSCCVSQLAVFVKETITSSPSTNGWEEEAMDRIVSVASTSTYLE
    

Molecular Weight10593.21 Da

Isoelectric Point (pI)9.05

Net Charge (pH 7.0)4.46

Net Charge (pH 7.4) 4.13

Charge Density (pH 7.0) 0.0469

GRAVY Index-0.06

Hydrophobic Moment 0.73

Boman Index-0.02

Instability Index44.53

Aliphatic Index 83.05

Aromaticity 0.0737

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4377.75

LogP -47.59

H-bond Donors 162.0

H-bond Acceptors 151.0

Rotatable Bonds 352.0

Heavy Atoms 738.0

Ring Count 12.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101391 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9925

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic