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MYP_117049
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Basic Information
Myxinidin (L6)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C58H92N16O17
Standard
Sequence
GIHDIAKYGKPS
Physicochemical Analysis
1285.45 Da
8.51
0.85
0.59
0.0704
-0.68
0.56
0.02
7.99
73.33
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
533.11
-4.75
18.0
19.0
41.0
91.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161772 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
20 μM
MIC
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0168910 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0170883 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
MIC
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0236776 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
50 μM
MIC
PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
RECORD: Rec_0248661 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
Vero cells is 0
PaperStructural insights into and activity analysis of the antimicrobial peptide myxinidin. Antimicrob Agents Chemother. 2014 Sep;58(9):5280-90. doi: 10.1128/AAC.02395-14. PMID: 24957834. PMID24957834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24957834/
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