Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC532H862N138O143S7

DescriptionStandard

        MESLAVGLFIIIAILLFQKPTVTEQLKTCWDNYVQGHCRKICRVNQVRDVLCENGRYFCLNIKELEACKKITKPPHPKPATLALTLPQDYVTITEKFPILKT
    

Molecular Weight11703.83 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0453

GRAVY Index0.02

Hydrophobic Moment 0.71

Boman Index0.06

Instability Index32.54

Aliphatic Index 105.10

Aromaticity 0.0784

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4508.34

LogP -32.53

H-bond Donors 158.0

H-bond Acceptors 157.0

Rotatable Bonds 387.0

Heavy Atoms 820.0

Ring Count 18.0

Amide Bonds 110.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0391923 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence