Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC425H656N114O126S9

DescriptionStandard

        ERCWKNNIGHCRKRCFHIERYKLLCMNKLSCCIPLTSDDPYTQWPIHPTLLEDVTAEFITRDDIPFTPVSGMDDSFTIEMTQ
    

Molecular Weight9667.03 Da

Isoelectric Point (pI)5.47

Net Charge (pH 7.0)-2.95

Net Charge (pH 7.4) -3.38

Charge Density (pH 7.0) -0.0360

GRAVY Index-0.42

Hydrophobic Moment 0.48

Boman Index-0.05

Instability Index51.61

Aliphatic Index 70.12

Aromaticity 0.0976

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3845.15

LogP -34.40

H-bond Donors 138.0

H-bond Acceptors 135.0

Rotatable Bonds 311.0

Heavy Atoms 674.0

Ring Count 19.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022439 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyDefensin

Tax ID72004

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

RECORD: Rec_0195915 VERIFIED: NO