Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC345H555N97O93S9

DescriptionStandard

        MTQLLLLIVALLVLGHVPPGRSEFKRCWKGQGACRTYCTRHETYMHMCPDASLCCVAYGIRPLPSKTESV
    

Molecular Weight7838.28 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.24

Charge Density (pH 7.0) 0.0529

GRAVY Index0.12

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index65.23

Aliphatic Index 87.71

Aromaticity 0.0714

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2994.80

LogP -25.87

H-bond Donors 112.0

H-bond Acceptors 109.0

Rotatable Bonds 250.0

Heavy Atoms 544.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023059 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0062387 VERIFIED: NO

Provenance & Taxonomy

OrganismPuma concolor (Mountain lion) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin