Peptide Database

Peptide NameHyposin-H6 (HPS-H6) (Hyposin HA-6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC70H130N22O15

DescriptionStandard

        LRPAILVRVKGKGL
    

Molecular Weight1519.92 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2684

GRAVY Index0.49

Hydrophobic Moment 0.29

Boman Index0.03

Instability Index44.06

Aliphatic Index 160.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 608.67

LogP -3.23

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 52.0

Heavy Atoms 107.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082102 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyHyposin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0135639 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyHyposin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0183335 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetXanthomonas axonopodis pv. glycines

Activity42 μM

MethodMIC

RECORD: Rec_0223705 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyHyposin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetX. axonopodis (Gram-negative)

RECORD: Rec_0316656 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyHyposin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)