Peptide Database

Peptide NameefeB signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory expression optimization

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase ▸ Xylanase

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC212H353N63O62S2

DescriptionStandard

        MSDEQKKPEQIHRRDILKWGAMAGAAVAIGASGLGGLAPLVQTAAKP
    

Molecular Weight4840.59 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.59

Net Charge (pH 7.4) 1.31

Charge Density (pH 7.0) 0.0339

GRAVY Index-0.12

Hydrophobic Moment 0.54

Boman Index0.08

Instability Index46.65

Aliphatic Index 89.57

Aromaticity 0.0213

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1987.06

LogP -20.10

H-bond Donors 67.0

H-bond Acceptors 67.0

Rotatable Bonds 162.0

Heavy Atoms 339.0

Ring Count 6.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030718 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyTat signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Alkaline active xylanase (XynBYG) secretion

TargetBacillus subtilis WB700

Activity0.0 U/mL

MethodXylanase activity assay

RECORD: Rec_0341960 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilyTat signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization L-Asparaginase secretion

TargetBacillus subtilis WB600

Activity9.1 U/mL

MethodAsparaginase activity assay

PaperFeng Y, Liu S, Jiao Y, et al. Enhanced extracellular production of L-asparaginase from Bacillus subtilis 168 by B-subtilis WB600 through a combined strategy[J]. Applied Microbiology and Biotechnology, 2017, 101(4): 1509-1520 PMID27796436 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27796436/