Peptide Database

Peptide NameFd

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC140H190N38O22

DescriptionStandard

        GFRKFHKFWAGFRKFHKFWAK
    

Molecular Weight2757.25 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.93

Net Charge (pH 7.4) 6.62

Charge Density (pH 7.0) 0.3300

GRAVY Index-0.81

Hydrophobic Moment 0.75

Boman Index-0.11

Instability Index17.76

Aliphatic Index 9.52

Aromaticity 0.3810

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 988.16

LogP -1.60

H-bond Donors 37.0

H-bond Acceptors 31.0

Rotatable Bonds 89.0

Heavy Atoms 200.0

Ring Count 12.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044547 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyFd

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Other ModsDidehydrophenylalanine (ΔF)

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium falciparum 3D7

Activity1.5±0.08 μM

MethodIC50; Fluorimetry (SYBR Green I)