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MYP_116887
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Basic Information
FLP-7
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
12 amino acids
C57H95N19O17S2
Standard
Sequence
SPMQRSSMVRFG
Physicochemical Analysis
1382.61 Da
12.00
1.46
1.25
0.1217
-0.51
0.15
-0.19
85.88
24.17
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
602.21
-7.96
22.0
21.0
45.0
95.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0197545 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FLP
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11:Phenylalanine amide
Bio-Activity Profile
Neuropeptide Neuromodulator Receptor modulation
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for FLP-7 (Caenorhabditis elegans): PMID 16377032,28128367,17564681 PMID16377032;28128367;17564681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16377032/
RECORD: Rec_0247944 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FMRFamide related peptide
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PaperImpaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry PMID17564681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17564681/
RECORD: Rec_0325765 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0426636 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FLP
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11:Phenylalanine amide
Bio-Activity Profile
Neuropeptide Neuromodulator Receptor modulation
and activating the npr-22 receptor which leads to induction of the atgl-1 lipase and subsequent fat loss (PubMed:33078707)
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for FLP-7 (Caenorhabditis elegans): PMID 33078707,17564681 PMID33078707;17564681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33078707/