Peptide Database

Peptide NameBrevinin-2Tb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC355H580N96O113S6

DescriptionStandard

        MFTMKKSLLLFFFLGTISLSLCQEERNADEDDGEMTEEEKRGILDTLKHLAKTAGKGALQSLLNHASCKLSGQC
    

Molecular Weight8193.37 Da

Isoelectric Point (pI)5.58

Net Charge (pH 7.0)-2.34

Net Charge (pH 7.4) -2.72

Charge Density (pH 7.0) -0.0316

GRAVY Index-0.24

Hydrophobic Moment 0.69

Boman Index-0.01

Instability Index38.51

Aliphatic Index 85.81

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3399.20

LogP -34.89

H-bond Donors 120.0

H-bond Acceptors 119.0

Rotatable Bonds 290.0

Heavy Atoms 570.0

Ring Count 6.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312905 VERIFIED: NO

Provenance & Taxonomy

OrganismRana temporaria [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence