Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC456H703N131O139S11

DescriptionStandard

        MKFSRVALAAAVVIACVCFLQTAAFPFTQETEDEHHVESETPQENEHLTETSQEQTNPNPLAFFRVKRQSHLSLCRYCCNCCRNKGCGYCCKF
    

Molecular Weight10596.97 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.82

Charge Density (pH 7.0) -0.0132

GRAVY Index-0.32

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index52.56

Aliphatic Index 56.67

Aromaticity 0.0968

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4363.87

LogP -49.10

H-bond Donors 158.0

H-bond Acceptors 153.0

Rotatable Bonds 345.0

Heavy Atoms 737.0

Ring Count 17.0

Amide Bonds 103.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0404252 VERIFIED: NO

Provenance & Taxonomy

OrganismPercocypris pingi [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence