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MYP_116699
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Basic Information
M-myrmeciitoxin-Mp2b
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
23 amino acids
C111H205N29O28S2
Standard
Sequence
LIGLVSKGTCVLVKTVCKKVLKQ
Physicochemical Analysis
2458.12 Da
9.90
4.74
4.50
0.2059
0.86
0.63
0.17
0.55
147.83
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.40
-6.64
35.0
35.0
88.0
170.0
0.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218894 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Haemonchus contortus
65.5
IC50
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
RECORD: Rec_0225539 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells
>15 μM
Killing
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
RECORD: Rec_0255225 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae ATCC 700677
9.6 μM
MIC
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
RECORD: Rec_0265126 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Formicidae venom precursor-01; Ant pilosulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Cytolytic Toxin Hemolytic Insecticidal
H. contortus
PaperThe Biochemical Toxin Arsenal from Ant Venoms PMID15019477;26805882;32629771;28513074 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15019477/
RECORD: Rec_0345331 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NRS 1
9.6 μM
MIC
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
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