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MYP_116699
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Basic Information
M-myrmeciitoxin-Mp2b
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
23 amino acids
C111H205N29O28S2
Standard
Sequence
LIGLVSKGTCVLVKTVCKKVLKQ
Physicochemical Analysis
2458.12 Da
9.90
4.74
4.50
0.2059
0.86
0.63
0.17
0.55
147.83
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.40
-6.64
35.0
35.0
88.0
170.0
0.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094749 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
<50 μM
MIC
PaperMolecular cloning and biological characterization of novel antimicrobial peptides, pilosulin 3 and pilosulin 4, from a species of the Australian ant genus Myrmecia.
RECORD: Rec_0125433 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
>15 μM
HC50
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
RECORD: Rec_0181360 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus VRSA1
9.6 μM
MIC
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
RECORD: Rec_0184729 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Formicidae venom precursor-01; Ant pilosulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Cytolytic Toxin Hemolytic Insecticidal
D. melanogaster
PaperThe Biochemical Toxin Arsenal from Ant Venoms PMID15019477;26805882;32629771;28513074 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15019477/
RECORD: Rec_0203621 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii ATCC 19606
9.6 μM
MIC
PMID28513074;32629771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28513074/
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