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MYP_116673
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Basic Information
HBsAg aa 202-213
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
12 amino acids
C67H97N15O20
Standard
Sequence
IPQSLDSWWTSL
Physicochemical Analysis
1432.58 Da
4.05
-1.24
-1.44
-0.1032
-0.12
0.44
0.24
62.96
97.50
0.1667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
567.52
-4.08
20.0
19.0
41.0
102.0
5.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153890 VERIFIED: YES
Provenance & Taxonomy
Hepatitis C virus [Virus]
Virus-derived peptide
3052230;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Hepatitis C virus (Translation); Huh7
Luciferase assay
PaperAmino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. | Li D, Takyar ST, Lott WB, Gowans EJ. | J Gen Virol. 2003 | PMID:12655082 PMID12655082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12655082/
RECORD: Rec_0229246 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 41.7%, C 58.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0233964 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory
PaperGupta S, Sharma AK, Shastri V, Madhu MK, Sharma VK. Prediction of anti-inflammatory proteins/peptides: an insilico approach. J Transl Med. 2017;15:7. PMID:28057002. https://pubmed.ncbi.nlm.nih.gov/28057002/ PMID28057002 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28057002/
RECORD: Rec_0303687 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory
T cell assay
PaperBalachandran Manavalan et al. AIPpred: Sequence-Based Prediction of Anti-inflammatory Peptides Using Random Forest. Front Pharmacol. 2018. PMID: 29636690. https://pubmed.ncbi.nlm.nih.gov/29636690/ ; https://pmc.ncbi.nlm.nih.gov/articles/PMC5881105/ PMID29636690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29636690/