Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC188H311N61O50S7

DescriptionStandard

        SGISGPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
    

Molecular Weight4450.31 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)5.40

Net Charge (pH 7.4) 5.10

Charge Density (pH 7.0) 0.1286

GRAVY Index0.12

Hydrophobic Moment 0.69

Boman Index0.04

Instability Index48.79

Aliphatic Index 67.14

Aromaticity 0.0476

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1751.11

LogP -21.34

H-bond Donors 68.0

H-bond Acceptors 63.0

Rotatable Bonds 138.0

Heavy Atoms 306.0

Ring Count 8.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352287 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0376123 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitystereochemistry not specified [Other]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity10-300 μg/mL

MethodMIC

RECORD: Rec_0383355 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 35.7%, T 35.7%, C 28.6% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative

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