MYP_116631
Basic Information
Gallidermin
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Standard
22 amino acids
C99H153N25O30S4
Standard
Sequence
IASKFLCTPGCAKTGSFNSYCC
Physicochemical Analysis
2301.68 Da
8.52
1.72
1.45
0.0781
0.40
0.30
0.19
20.50
44.55
0.1364
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
882.14
-11.50
35.0
36.0
71.0
158.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0366369 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus gallinarum Tu3928,Staphylococcus cohnii T [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Propionibacterium acnes IF 31002
0.125 μg/mL
MIC
RECORD: Rec_0369366 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus gallinarum [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Gallidermin differs from StT (a natural variant of this peptide) only by one base in the nucleotide sequence for the leader sequence. However, there is no difference at the amino acid level (Furmanek B et al. 1999 J Appl Microbiol 87: 856-866). Thus, they are treated as identical peptide in this database. Chemical modification: Gallidermin contains four thioether rings (S3-C7, T8-C11, S16-C21, and S19-C22) and dehydrated T14
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis ATCC 12228
4 μg/mL
MIC
RECORD: Rec_0373194 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus gallinarum [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Gallidermin differs from StT (a natural variant of this peptide) only by one base in the nucleotide sequence for the leader sequence. However, there is no difference at the amino acid level (Furmanek B et al. 1999 J Appl Microbiol 87: 856-866). Thus, they are treated as identical peptide in this database. Chemical modification: Gallidermin contains four thioether rings (S3-C7, T8-C11, S16-C21, and S19-C22) and dehydrated T14
Bio-Activity Profile
Antimicrobial
C. xerosis ATCC 9755
1 μg/mL
MIC
RECORD: Rec_0378639 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus gallinarum [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Gallidermin differs from StT (a natural variant of this peptide) only by one base in the nucleotide sequence for the leader sequence. However, there is no difference at the amino acid level (Furmanek B et al. 1999 J Appl Microbiol 87: 856-866). Thus, they are treated as identical peptide in this database. Chemical modification: Gallidermin contains four thioether rings (S3-C7, T8-C11, S16-C21, and S19-C22) and dehydrated T14
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 11775
128 μg/mL
MIC
RECORD: Rec_0404612 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus gallinarum [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
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