MYP_116603
Potassium channel toxin alpha-KTx 2.15
Membrane / Ion-channel modulation
▸
Ion channel modulation
Venom / Toxin
▸
General toxin
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Toxin
Standard
38 amino acids
C180H292N52O47S6
Standard
IFINVKCSSPQQCLKPCKKAFGQHAGGKCINGKCKCYP
4128.95 Da
9.42
6.78
6.43
0.1784
-0.31
0.59
-0.03
30.70
53.95
0.0789
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1600.61
-17.33
58.0
61.0
138.0
285.0
7.0
42.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0011087
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Potassium channel blocker
Kv1.2/KCNA2
0.0003 μM
IC50
RECORD: Rec_0132887
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Shaker IR
0.012 μM
IC50
RECORD: Rec_0255401
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Potassium channel blocker
Kv1.3/KCNA3
0.0083 μM
IC50
RECORD: Rec_0282403
VERIFIED: YES
Provenance & Taxonomy
Centruroides tecomanus [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 13-34; 17-36
Bio-Activity Profile
Toxin
Ion channel blocker
Potassium channel blocker
potassium channel KCa3.1/KCNN4
0.0064 μM
IC50