Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC722H1166N206O217S14

DescriptionStandard

        MQDHLKHILLEYHKTCGLSSPKKSFTMKILLFFSTFLFFGVFIPPVGSGQTIGNSDSSSKIMCRRKLETLYSEARNSSTTSENTQYGTEENKTAKRKEHTVALNRRLACTMLGGQCKNKCGEKEFRIIYCERPTTLCCMRECDSKK
    

Molecular Weight16653.14 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)9.78

Net Charge (pH 7.4) 9.18

Charge Density (pH 7.0) 0.0670

GRAVY Index-0.53

Hydrophobic Moment 0.64

Boman Index-0.13

Instability Index58.54

Aliphatic Index 62.12

Aromaticity 0.0822

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6910.24

LogP -77.12

H-bond Donors 254.0

H-bond Acceptors 245.0

Rotatable Bonds 573.0

Heavy Atoms 1159.0

Ring Count 20.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228060 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence