Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length439 amino acids

Chemical FormulaC2168H3499N563O619S15

DescriptionStandard

        AGRAIGIESLQQKLRTIQLKDVSGTEKLDIGKVEYSITGMQIVNLGLPKSALRLVPGTGVMLSVGDAYISLRGNWRVKYSWIIKASGSFELAVSELAISTIIAVKSDVTGRPTVSVTKCEAAVGSVKVRFHGGASWLYNLFDSFINKALRNALQKQICSLVTASIAEMNHNLKTLNVLAKVDQYAELEYSMVESPVISNAMIDLGLKGEFYNIGPHEEPPFSPRPFLLPSQDTNMLYIGVSAFSINSAGFVYHRAGALRLYITDDMIPSGSLNRLNTKTFGKFIPQIAKMSPGLMMKLLVETVKEPIITLEPNNMTVQASSKVTAYAIQPNSILSPLFVLRLEASVSAHIYVTGLKLAGHVTLNKIDMSLAESYVGPFQVRSLEDIFTTVVKDVIIPKVNAGVKQGYPLPAIGKMQLVKSHLQVLKNYLLIGTDVKFTG
    

Molecular Weight47836.35 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)11.41

Net Charge (pH 7.4) 10.73

Charge Density (pH 7.0) 0.0260

GRAVY Index0.19

Hydrophobic Moment 0.72

Boman Index0.15

Instability Index34.54

Aliphatic Index 108.34

Aromaticity 0.0752

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 38975.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038535 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus rhinocerous [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria