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MYP_116533
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Basic Information
Histatin-3 (Basic histidine-rich protein) (Hst) (Histidine-rich protein 3) (PB) [Cleaved into: Histatin-3; His3-(20-44)-peptide (His3 20 44) (His3-(1-25)-peptide) (His3 1 25) (Histatin-3 1 25) (Histatin-6); His3-(20-43)-peptide (His3 20 43) (His3-(1-24)-peptide) (His3 1 24) (Histatin-3 1 24) (Histatin-5); His3-(20-32)-peptide (His3 20 32) (His3-(1-13)-peptide) (His3 1 13) (Histatin-3 1 13); His3-(20-31)-peptide (His3 20 31) (His3-(1-12)-peptide) (His3 1 12) (Histatin-3 1 12); His3-(20-30)-peptide (His3 20 30) (His3-(1-11)-peptide) (His3 1 11) (Histatin-3 1 11); His3-(24-32)-peptide (His3 24 32) (His3-(5-13)-peptide) (His3 5 13) (Histatin-3 5 13); His3-(24-31)-peptide (His3 24 31) (His3-(5-12)-peptide) (His3 5 12) (Histatin-11) (Histatin-3 5 12); His3-(24-30)-peptide (His3 24 30) (His3-(5-11)-peptide) (His3 5 11) (Histatin-12) (Histatin-3 5 11); His3-(25-32)-peptide (His3 25 32) (His3-(6-13)-peptide) (His3 6 13) (Histatin-3 6 13); His3-(25-30)-peptide (His3 25 30) (His3-(6-11)-peptide) (His3 6 11) (Histatin-3 6 11); His3-(26-32)-peptide (His3 26 32) (His3-(7-13)-peptide) (His3 7 13) (Histatin-3 7 13); His3-(26-31)-peptide (His3 26 31) (His3-(7-12)-peptide) (His3 7 12) (Histatin-3 7 12); His3-(26-30)-peptide (His3 26 30) (His3-(7-11)-peptide) (His3 7 11) (Histatin-3 7 11); His3-(31-51)-peptide (His3 31 51) (His3-(12-32)-peptide) (His3 12 32) (Histatin-3 12 32) (Histatin-4); His3-(31-44)-peptide (His3 31 44) (His3-(12-25)-peptide) (His3 12 25) (Histatin-3 12 25) (Histatin-9); His3-(31-43)-peptide (His3 31 43) (His3-(12-24)-peptide) (His3 12 24) (Histatin-3 12 24) (Histatin-7); His3-(32-44)-peptide (His3 32 44) (His3-(13-25)-peptide) (His3 13 25) (Histatin-10) (Histatin-3 13 25); His3-(32-43)-peptide (His3 32-43) (His3-(13-24)-peptide) (His3 13 24) (Histatin-3 13 24) (Histatin-8); His3-(33-44)-peptide (His3 33 44) (His3-(14-25)-peptide) (His3 14 25) (Histatin-3 14 25); His3-(33-43)-peptide (His3 33 43) (His3-(14-24)-peptide) (His3 14 24) (Histatin-3 14 24); His3-(34-44)-peptide (His3 34 44) (His3-(15-25)-peptide) (His3 15 25) (Histatin-3 15 25); His3-(34-43)-peptide (His3 34 43) (His3-(15-24)-peptide) (His3 15 24) (Histatin-3 15 24); His3-(45-51)-peptide (His3 45 51) (His3-(26-32)-peptide) (His3 26 32) (Histatin-3 26 32); His3-(47-51)-peptide (His3 47 51) (His3-(28-32)-peptide) (His3 28 32) (Histatin-3 28 32); His3-(48-51)-peptide (His3 48 51) (His3-(29-32)-peptide) (His3 29 32) (Histatin-3 29 32)]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C279H418N84O69S3
Standard
Sequence
MKFFVFALILALMLSMTGADSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN
Physicochemical Analysis
6149.02 Da
10.09
6.11
5.52
0.1197
-0.70
0.41
-0.12
31.27
59.41
0.1569
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2476.93
-20.06
90.0
85.0
205.0
435.0
15.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042977 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin statherin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Non-hemolytic
C. neoformans
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID2719677;3426601;2344289;8336540;15489334;7951254;3286634;2372245;15272024;8945538;11226423;11179305;12761219;14966203;17503797;20973643 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2719677/
RECORD: Rec_0065428 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPatent US 2008/0269122 A1 Evidence URLhttps://patents.google.com/patent/US20080269122A1/en PatentUS 2008/0269122 A1
RECORD: Rec_0068203 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Histatin
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7388
RECORD: Rec_0253878 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Histatin statherin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Non-hemolytic
Candida albicans
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID2719677;3426601;2344289;8336540;15489334;7951254;3286634;2372245;15272024;8945538;11226423;11179305;12761219;14966203;17503797;20973643 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2719677/
RECORD: Rec_0395748 VERIFIED: NO
Provenance & Taxonomy
Pan paniscus [Animal]
Histatin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7389