Peptide Database

Peptide NameBovine tracheal antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC171H291N65O42S6

DescriptionStandard

        NHVTCRINRGFCVPIRCPGHRRQIGTCLGPRIKCCR
    

Molecular Weight4121.94 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.48

Charge Density (pH 7.0) 0.2187

GRAVY Index-0.34

Hydrophobic Moment 0.76

Boman Index-0.24

Instability Index33.41

Aliphatic Index 70.28

Aromaticity 0.0278

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1741.86

LogP -20.54

H-bond Donors 69.0

H-bond Acceptors 58.0

Rotatable Bonds 133.0

Heavy Atoms 284.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217125 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)