Peptide Database

Peptide NameBeta-defensin 135 (Defensin, beta 135; Human, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC275H442N76O71S6

DescriptionStandard

        GPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVNPKYLPILTGK
    

Molecular Weight6141.31 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.78

Net Charge (pH 7.4) 5.43

Charge Density (pH 7.0) 0.1091

GRAVY Index-0.12

Hydrophobic Moment 0.66

Boman Index0.00

Instability Index35.50

Aliphatic Index 93.77

Aromaticity 0.0943

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2376.38

LogP -18.95

H-bond Donors 87.0

H-bond Acceptors 84.0

Rotatable Bonds 199.0

Heavy Atoms 428.0

Ring Count 11.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025638 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0301604 VERIFIED: NO