Peptide Database

Peptide NameHIV-1 TAT peptide--Crystallins

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC65H124N34O15

DescriptionStandard

        GRKKRRQRRRPQ
    

Molecular Weight1621.90 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.6465

GRAVY Index-3.65

Hydrophobic Moment 0.48

Boman Index-1.61

Instability Index227.68

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 884.25

LogP -11.76

H-bond Donors 34.0

H-bond Acceptors 23.0

Rotatable Bonds 60.0

Heavy Atoms 114.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0114052 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

FamilyTat

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0341054 VERIFIED: NO