Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length475 amino acids

Chemical FormulaC2432H3908N632O677S21

DescriptionStandard

        MKSCVVIFFLVSLISSDTAAPPPGIKVRITEKVKDLGLMYLKGLVNREFLIENEDFLIKSVTLTKLQIDPAQVDFRFQDKIGLQFEIRDLNFALQLQREKNVQFFKKFKIDKGTTIFTGEGVRAMILVRMNQNPKGHLNVEIGKEDCKINADSIRTKSTGFVGKVLDKFKSLTKHFFKKKICPALQPMINDKLKDLSTMRTVHEGRQLDLDYSLSSDIAVTSRSLDMSFKGLLSVHGKAVDPGSIRPGREPVFTETNKMVYVGISEFFFNGAAMAIYKSGPFEFNVPEMEGLLVGLGQKIMEIKPGPWTAELIEAPIIEISNDDLSATAYFKAQRKAKLNGFLMTCRFKMDIEFKERLLIMNIQEPKCKEKAGKIKGKFLVRRQCSNRFTSISLYQQIFIIIIIIIIITCVSLFVQAFLVNVFHERITKSLVKEIPIPLPAELSLINATNQFEEGYLVVGGSLTFNPQNSSNAGG
    

Molecular Weight53506.24 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)14.92

Net Charge (pH 7.4) 14.21

Charge Density (pH 7.0) 0.0314

GRAVY Index0.00

Hydrophobic Moment 0.75

Boman Index0.07

Instability Index24.58

Aliphatic Index 99.31

Aromaticity 0.0905

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338510 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria