Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC348H561N107O103S3

DescriptionStandard

        QHWSHGWYPGGKRELDMPASPEVSEEIKLCEGEECAYLRNPRKNLLKNILGRSNQKKNADVLARQLQKK
    

Molecular Weight7988.03 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.93

Net Charge (pH 7.4) 3.57

Charge Density (pH 7.0) 0.0569

GRAVY Index-1.12

Hydrophobic Moment 0.60

Boman Index-0.27

Instability Index75.25

Aliphatic Index 70.72

Aromaticity 0.0580

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3458.45

LogP -34.95

H-bond Donors 119.0

H-bond Acceptors 112.0

Rotatable Bonds 275.0

Heavy Atoms 561.0

Ring Count 12.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0332629 VERIFIED: YES

Provenance & Taxonomy

OrganismAquarana catesbeiana [Animal]

FamilyProgonadoliberin

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour