Peptide Database

Peptide NameIL-31

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC695H1136N188O222S5

DescriptionStandard

        SHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT
    

Molecular Weight15837.91 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-6.19

Net Charge (pH 7.4) -6.69

Charge Density (pH 7.0) -0.0439

GRAVY Index-0.31

Hydrophobic Moment 0.81

Boman Index-0.03

Instability Index72.69

Aliphatic Index 101.63

Aromaticity 0.0355

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6614.71

LogP -67.79

H-bond Donors 224.0

H-bond Acceptors 225.0

Rotatable Bonds 534.0

Heavy Atoms 1110.0

Ring Count 18.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032177 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPredicted N-linked glycosylation of asparagine residues at positions 44 and 77

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-31 receptor (Human)