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MYP_116290
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C76H130N18O20
Standard
Sequence
FLGAIAQALTSLLGKL
Physicochemical Analysis
1615.95 Da
8.75
0.76
0.55
0.0474
1.38
0.46
0.51
-6.54
165.00
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
609.39
-3.72
21.0
21.0
54.0
114.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038365 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0104485 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the Italian stream frog Rana italica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
α-amidated residue at the C-terminus
Bio-Activity Profile
Antimicrobial Anticancer
A549
45 μM
LC50
PaperPubMed PMID: 28699258 PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
RECORD: Rec_0135610 VERIFIED: NO
Provenance & Taxonomy
Rana italica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis and fungus, Candida parapsilosis
RECORD: Rec_0189097 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the Italian stream frog Rana italica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
α-amidated residue at the C-terminus
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
mouse erythrocytes
22 μM
LC50
PaperPubMed PMID: 28699258 PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
RECORD: Rec_0223079 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the Italian stream frog Rana italica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
α-amidated residue at the C-terminus
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
100 μM
LC50
PaperPubMed PMID: 28699258 PMID28699258 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28699258/
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