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MYP_116289
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Basic Information
L4K5W2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C76H126N18O12
Standard
Sequence
LLKWLKKWLKK
Physicochemical Analysis
1483.93 Da
10.60
4.76
4.54
0.4323
-0.55
0.78
-0.15
8.37
141.82
0.1818
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
516.00
2.52
19.0
17.0
53.0
106.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254436 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
2.5 μg/mL
MIC
PaperDe novo generation of short antimicrobial peptides with simple amino acid composition. Regul Pept. 2011 Jan 17;166(1-3):36-41. doi: 10.1016/j.regpep.2010.08.010. PMID: 20736034. PMID20736034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20736034/
RECORD: Rec_0285641 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20736034/ PMID20736034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20736034/
RECORD: Rec_0293578 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
aeruginosa
20 μg/mL
MIC
PaperDe novo generation of short antimicrobial peptides with simple amino acid composition. Regul Pept. 2011 Jan 17;166(1-3):36-41. doi: 10.1016/j.regpep.2010.08.010. PMID: 20736034. PMID20736034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20736034/
RECORD: Rec_0297452 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
pneumoniae
40 μg/mL
MIC
PaperDe novo generation of short antimicrobial peptides with simple amino acid composition. Regul Pept. 2011 Jan 17;166(1-3):36-41. doi: 10.1016/j.regpep.2010.08.010. PMID: 20736034. PMID20736034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20736034/
RECORD: Rec_0356206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (MRSA)
40 μg/mL
MIC
PaperDe novo generation of short antimicrobial peptides with simple amino acid composition. Regul Pept. 2011 Jan 17;166(1-3):36-41. doi: 10.1016/j.regpep.2010.08.010. PMID: 20736034. PMID20736034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20736034/
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