MYP_116277
galacardin B
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antiparasitic
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Antimalarial
Antiparasitic
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General antiparasitic
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Antiparasitic
Delivery / Targeting
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Cell penetration
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Cell-penetrating peptide
Delivery / Targeting
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Drug delivery vehicle
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
XXXXXXXXXXXXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0048701
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
galacardin
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Non-proteinogenic/modified monomers: NMe-Hpg; D-Gal; Rha; bOH-Tyr; D-Man; Hpg; Cl-Hpg; bOH-Cl-Tyr; Dhpg; Ria; D-Glc
Bio-Activity Profile
Antimicrobial
Anti-Gram-positive
RECORD: Rec_0064589
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic peptide
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Methylation
None
R1=CH3CHCH3CH2CH3, R2=, R3=CH3CHCH3CH2CH3, R4=NH(CH3), hydroxyproline
Bio-Activity Profile
Antimicrobial
Antiparasitic
Antimalarial
Plasmodium falciparum K1
3.7 μM
IC50; [3H] Hypoxanthine incorporation assay
RECORD: Rec_0121839
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
5(6)-Carboxyfluorescein
Amidation
Z=NLys from N-tert-butoxycarbonyl-1,4-butanediamine; X=NLeu from isobutylamine
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
RECORD: Rec_0135659
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polylysine
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Fluorescein/FITC labeling
Amidation
Peptoids (poly-N-substituted glycines)
Bio-Activity Profile
Cargo delivery
RECORD: Rec_0232670
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cyclic peptide
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Methylation
None
R1=C6H6CH2CH3, R2=CH(CH3)2, R3=CH3, R4=N+(CH3)3I-
Bio-Activity Profile
Antimicrobial
Antiparasitic
Antimalarial
Plasmodium falciparum K1
10.3 μM
IC50; [3H] Hypoxanthine incorporation assay
Showing 5 records on this page · Page 1 of 2