Peptide Database

Peptide Namelarge neurotensin

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC729H1170N204O217S6

DescriptionStandard

        DSEEEMKALEADFLTNMHTSKISKAHVPSWKMTLLNVCSLVNNLNSPAEETGEVHEEELVARRKLPTALDGFSLEAMLTIYQLHKICHSRAFQHWELIQEDILDTGNDKNGKEEVIKRKIPYILKRQLYENKPRRPYILKR
    

Molecular Weight16456.72 Da

Isoelectric Point (pI)6.66

Net Charge (pH 7.0)-0.70

Net Charge (pH 7.4) -1.29

Charge Density (pH 7.0) -0.0050

GRAVY Index-0.63

Hydrophobic Moment 0.73

Boman Index-0.12

Instability Index57.70

Aliphatic Index 89.93

Aromaticity 0.0638

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6843.75

LogP -60.10

H-bond Donors 236.0

H-bond Acceptors 228.0

Rotatable Bonds 564.0

Heavy Atoms 1156.0

Ring Count 23.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302950 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Vasoactive Signaling peptide Neuropeptide activity

TargetNTS1 receptor (Human)