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MYP_116236
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C16H20N4O4
Standard
Sequence
GAW
Physicochemical Analysis
332.35 Da
5.53
-0.24
-0.44
-0.0800
0.17
0.17
0.64
-21.63
33.33
0.3333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
137.31
-0.26
5.0
4.0
7.0
24.0
2.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020492 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
240 μM
IC50
PaperPurification of angiotensin I-converting enzyme inhibitory peptides and antihypertensive effect of milk produced by protease-facilitated lactic fermentation | Chen, G-W. et al. | DOI: 10.1016/j.idairyj.2006.07.004 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0146865 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Inhibitor
PaperKashima A., Inoue Y., Sugio S., Maeda I., Nose T., Shimohigashi Y.. X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction. Eur. J. Biochem., 255, 12-23, 1998.
RECORD: Rec_0242081 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperImpact of milk processing on the generation of peptides during digestion
RECORD: Rec_0247408 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0253435 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
240.0 μM
IC50
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