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MYP_116192
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
6 amino acids
C38H50N6O10
Standard
Sequence
YPVEPF
Physicochemical Analysis
750.84 Da
4.05
-1.24
-1.44
-0.2064
-0.17
0.39
0.34
125.20
48.33
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
248.77
0.55
7.0
9.0
17.0
54.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0176558 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
138 μM
IC50
PaperIdentification of novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides in camel milk protein hydrolysates | Nongonierma, A. et al. | DOI: 10.1016/j.foodchem.2017.10.033 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0181656 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Enzyme inhibitory DPP-IV Inhibitory
Dipeptidyl peptidase IV
124.7 μM
IC50
RECORD: Rec_0192095 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Mucin secretagogue
HT29-MTX cells
Paperβ-Casein(94-123)-derived peptides differently modulate production of mucins in intestinal goblet cells | Plaisancie, P. et al. | DOI: 10.1017/S0022029914000533 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0208298 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
and Listeria monocytogenes
PMID29915567 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29915567/
RECORD: Rec_0231731 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Neocasomorphin
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
PaperPeptidomic analysis reveals proteolytic activity of kefir microorganisms on bovine milk proteins; Enzymatic release of neocasomorphin and beta-casomorphin from bovine beta-casein PMID26616950;10503774 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26616950/
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