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MYP_116182
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Basic Information
Ceratotoxin-B
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C135H235N35O32
Standard
Sequence
SIGSAFKKALPVAKKIGKAALPIAKAALP
Physicochemical Analysis
2860.53 Da
10.70
5.45
5.24
0.1881
0.54
0.65
0.22
25.18
118.28
0.0345
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1048.33
-7.15
35.0
38.0
95.0
202.0
4.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018589 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
PMID8353519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8353519/
RECORD: Rec_0020436 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperMarchini D., Giordano P.C., Amons R., Bernini L.F., Dallai R.;. "Purification and primary structure of ceratotoxin A and B, two antibacterial peptides from the female reproductive accessory glands of the medfly Ceratitis capitata (Insecta:Diptera)."; Insect Biochem. Mol. Biol. 23:591-598. Evidence URLhttps://www.uniprot.org/uniprotkb/CERB_CERCA/entry
RECORD: Rec_0058714 VERIFIED: YES
Provenance & Taxonomy
Mediterranean fruit [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID8353519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8353519/
RECORD: Rec_0073918 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://patents.google.com/patent/US20030096949A1/en PatentUS 2003/0096949 A1
RECORD: Rec_0222516 VERIFIED: YES
Provenance & Taxonomy
Ceratitis capitata [Animal]
Ceratotoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anti-mammalian cells
PaperInsect Biochem. Mol. Biol. 1993; 23:591-598 | http://www.ncbi.nlm.nih.gov/pubmed/8353519 PMID8353519 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8353519/
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