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MYP_116160
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Basic Information
NKR-5-3B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
64 amino acids
C292H489N73O82
Standard
Sequence
LTANLGISSYAAKKVIDIINTGSAVATIIALVTAVVGGGLITAGIVATAKSLIKKYGAKYAAAW
Physicochemical Analysis
6334.45 Da
9.90
4.75
4.54
0.0743
0.95
0.62
0.40
9.52
134.38
0.0625
9970.00
9970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2455.00
-21.96
88.0
87.0
209.0
447.0
5.0
65.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0082287 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
Structure & Mods
head-to-tail backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
N-to-C backbone cyclization
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactococcus sp. QU 12
5.75 μM
MIC
PMID26174911 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26174911/
RECORD: Rec_0088076 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
Structure & Mods
head-to-tail backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
N-to-C backbone cyclization
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes ATCC BAA-679
0.693 μM
MIC
PMID26174911 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26174911/
RECORD: Rec_0119990 VERIFIED: NO
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
1351; 0
Structure & Mods
head-to-tail backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
N-to-C backbone cyclization
Bio-Activity Profile
Antimicrobial
PaperPDB 2MP8 structural record; NMR; chain A; residues 1-64 PMID26174911
RECORD: Rec_0121918 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
Structure & Mods
head-to-tail backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
N-to-C backbone cyclization
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus bovis JCM 5802
1.44 μM
MIC
PMID26174911 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26174911/
RECORD: Rec_0123327 VERIFIED: YES
Provenance & Taxonomy
Enterococcus faecium [Bacterium]
Bacteriocin
Structure & Mods
head-to-tail backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
N-to-C backbone cyclization
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactococcus lactis ssp. lactis IL1403
0.049 μM
MIC
PMID26174911 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26174911/
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