Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC474H732N134O133S10

DescriptionStandard

        MPIKMKYFTVLYMFAFFFVAVCYISQSSASPAPKEEANFVHGADALKQLEPESHGRYKRATCDLLSGTGVGHSACAAHCLLRGNRGGYCNGKGVCVCRN
    

Molecular Weight10756.35 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.78

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0483

GRAVY Index-0.01

Hydrophobic Moment 0.54

Boman Index0.08

Instability Index47.45

Aliphatic Index 67.07

Aromaticity 0.1111

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4246.09

LogP -44.08

H-bond Donors 155.0

H-bond Acceptors 152.0

Rotatable Bonds 348.0

Heavy Atoms 751.0

Ring Count 19.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389553 VERIFIED: NO

Provenance & Taxonomy

OrganismMusca domestica [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence