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MYP_116093
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Basic Information
FLP-18
Developmental biology ▸ Molting regulation
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
13 amino acids
C62H92N16O18S
Standard
Sequence
DFDGAMPGVLRFG
Physicochemical Analysis
1381.56 Da
4.21
-1.24
-1.44
-0.0952
0.23
0.52
0.23
55.01
60.00
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
540.23
-4.21
18.0
18.0
42.0
97.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016234 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FMRFamide related peptide
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
PaperImpaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry PMID17564681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17564681/
RECORD: Rec_0199824 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FLP
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator Myotropic Receptor modulation Immunomodulatory Sleep regulation Wake regulation Molting regulator
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for FLP-18 (Caenorhabditis elegans): PMID 28662030,17564681 PMID28662030;17564681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28662030/
RECORD: Rec_0211482 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
FLP
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator Myotropic Receptor modulation Immunomodulatory Sleep regulation Wake regulation Molting regulator
coupled receptor
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for FLP-18 (Caenorhabditis elegans): PMID 14555955,17564681 PMID14555955;17564681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14555955/
RECORD: Rec_0336642 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/