‹ ›
MYP_116031
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
22 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GFXGXKKXGXFXGXGKKXKKKK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0194018 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,5,8,10,12,14,18
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus USA 300
39.35 μM
MIC
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0209846 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,5,8,10,12,14,18
Bio-Activity Profile
Antimicrobial Antibacterial
Human prostate adenocarcinoma PC-3
7.5 μM
IC50
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0218468 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,5,8,10,12,14,18
Bio-Activity Profile
Antimicrobial Antibacterial
Neisseria gonorrhoeae ATCC 49226
0.61 μM
MIC
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0220992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 3,5,8,10,12,14,18
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae ATCC 49619
39.35 μM
MIC
PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
RECORD: Rec_0223468 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
X=A6c (1-aminocyclohexane carboxylic acid)
Bio-Activity Profile
Antimicrobial Anticancer
CFPAC-1
>7.5 μM
IC50
PaperAntibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(alpha) amino acids. Bioorg Med Chem. 2016 Sep 15;24(18):4056-4065. doi: 10.1016/j.bmc.2016.06.048. PMID: 27387357. PMID27387357 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27387357/
FIRST PREV 1 ... 3 4 5 6 7 ... 10 NEXT LAST
Showing 5 records on this page · Page 5 of 10