Peptide Database

Peptide NameHS014

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC59H87N19O17S2

DescriptionStandard

        CEHARWGCPPKD
    

Molecular Weight1398.57 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.17

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0139

GRAVY Index-1.36

Hydrophobic Moment 0.30

Boman Index-0.28

Instability Index74.08

Aliphatic Index 8.33

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 572.83

LogP -5.32

H-bond Donors 21.0

H-bond Acceptors 20.0

Rotatable Bonds 40.0

Heavy Atoms 97.0

Ring Count 5.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344200 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetMC1 receptor (Human); MC3 receptor (Human); MC4 receptor (Human)

Activity3.2 nM

MethodKi