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MYP_115942
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Basic Information
Temporin-1SPa
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
13 amino acids
C72H110N14O17
Standard
Sequence
FLSAITSILGKFF
Physicochemical Analysis
1443.73 Da
8.75
0.76
0.55
0.0584
1.55
0.48
0.59
17.52
127.69
0.2308
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
499.23
-1.73
18.0
18.0
46.0
103.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0251547 VERIFIED: YES
Provenance & Taxonomy
Lithobates septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Gram-negative and Gram-positive bacteria
PMID15556063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0300517 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus USA300
6.3 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
RECORD: Rec_0302625 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
25 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
RECORD: Rec_0308848 VERIFIED: NO
Provenance & Taxonomy
Rana septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
RECORD: Rec_0313353 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
PaperPubMed PMID: 15556063 PMID15556063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
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