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MYP_115942
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Basic Information
Temporin-1SPa
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
13 amino acids
C72H110N14O17
Standard
Sequence
FLSAITSILGKFF
Physicochemical Analysis
1443.73 Da
8.75
0.76
0.55
0.0584
1.55
0.48
0.59
17.52
127.69
0.2308
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
499.23
-1.73
18.0
18.0
46.0
103.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051869 VERIFIED: NO
Provenance & Taxonomy
Lithobates septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID15556063 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0060003 VERIFIED: NO
Provenance & Taxonomy
American frog [Animal]
Temporin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0100154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0105016 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBCs
37.5 μM
Hemolysis
PMID15556063;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0115193 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Antitumor Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 10231
25 μM
MIC
PMID15556063;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
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