Peptide Database

Peptide NamePal-ano-9 (Pal-anoplin peptide derivative)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC48H92N14O11

DescriptionStandard

        GLLKRIKTL
    

Molecular Weight1041.33 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.3065

GRAVY Index0.28

Hydrophobic Moment 0.56

Boman Index-0.06

Instability Index26.24

Aliphatic Index 173.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 430.29

LogP -2.01

H-bond Donors 16.0

H-bond Acceptors 14.0

Rotatable Bonds 38.0

Heavy Atoms 73.0

Ring Count 0.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123176 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcylation (Gly1 conjugated with a palmitoyl group)

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEscherichia coli ATCC 25922

Activity0.406 μg/mL

MethodMIC

RECORD: Rec_0165556 VERIFIED: YES

Provenance & Taxonomy

OrganismAnoplius samariensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermC16

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

Targethuman RBC

Activity18.92 μg/mL

MethodHC50

RECORD: Rec_0241428 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcylation (Gly1 conjugated with a palmitoyl group)

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

Targethuman red blood cells

RECORD: Rec_0340802 VERIFIED: YES

Provenance & Taxonomy

OrganismAnoplius samariensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermC16

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans ATCC 10231

Activity3.25 μg/mL

MethodMIC

RECORD: Rec_0414256 VERIFIED: YES

Provenance & Taxonomy

OrganismAnoplius samariensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermC16

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetE coli ATCC 25922

Activity0.406 μg/mL

MethodMIC

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