Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC274H416N82O82S6

DescriptionStandard

        AVPFSEVLTEEVGSFNSPVGEHQQPGGESMRLPEPFRFKRQSHLSLCRWCCNCCHN
    

Molecular Weight6363.12 Da

Isoelectric Point (pI)6.30

Net Charge (pH 7.0)-0.98

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0174

GRAVY Index-0.54

Hydrophobic Moment 0.49

Boman Index-0.07

Instability Index92.40

Aliphatic Index 50.36

Aromaticity 0.0893

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2619.27

LogP -29.93

H-bond Donors 93.0

H-bond Acceptors 90.0

Rotatable Bonds 202.0

Heavy Atoms 444.0

Ring Count 14.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0158032 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyHepcidin

Tax ID8032

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal