Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC610H982N172O186S8

DescriptionStandard

        MRLLLLALPILVLLPQVIPAYSGEKKCWNKSGHCRKQCIDEEVMQEKCTNHRACCVPESKRDRQVPKTPSTLSHDLPSSAPFDVISTPVPTTYGFVVTSKEVTVNQSEEVHATEISHPKVHHSSE
    

Molecular Weight13957.88 Da

Isoelectric Point (pI)7.04

Net Charge (pH 7.0)0.08

Net Charge (pH 7.4) -0.62

Charge Density (pH 7.0) 0.0006

GRAVY Index-0.38

Hydrophobic Moment 0.56

Boman Index-0.04

Instability Index62.06

Aliphatic Index 80.96

Aromaticity 0.0400

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5687.70

LogP -60.45

H-bond Donors 199.0

H-bond Acceptors 201.0

Rotatable Bonds 454.0

Heavy Atoms 976.0

Ring Count 24.0

Amide Bonds 132.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078868 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence