MYP_115761
Basic Information
Mu-theraphotoxin-Hhn2a
Annotation / Sequence feature Nuclear export signal
Anticancer Cytotoxic anticancer activity Cytotoxic
Membrane / Ion-channel modulation Ion channel inhibition
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin huwentoxin-1 family
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
Venom / Toxin Toxin
Standard
33 amino acids
C154H233N43O46S6
Standard
Sequence
GCKGFGDSCTPGKNECCPNYACSSKHKWCKVYL
Physicochemical Analysis
3615.15 Da
8.63
2.78
2.43
0.0844
-0.62
0.36
-0.08
77.94
23.64
0.1212
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1433.67
-17.33
55.0
56.0
115.0
249.0
8.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126858 VERIFIED: YES
Provenance & Taxonomy
Haplopelma hainanum [Animal]
huwentoxin-1 family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
2-17; 9-22; 16-29
Bio-Activity Profile
Toxin Venom huwentoxin-1 family Ion channel inhibitor Pathogenesis-associated
RECORD: Rec_0194979 VERIFIED: NO
Provenance & Taxonomy
Selenocosmia hainana,Haplopelma hainanum,Ornithoctonus hainana [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
2-17; 9-22; 16-29
Bio-Activity Profile
Toxin
RECORD: Rec_0282088 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 24.2%, T 36.4%, C 39.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic