Peptide Database

Peptide NameHemocyte defensin Cg-Defh2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC274H437N79O80S10

DescriptionStandard

        LLTLAVLLMVSADMAFAGFGCPGDQYECNRHCRSIGCRAGYCDAVTLWLRCTCTGCSGKK
    

Molecular Weight6438.53 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.39

Charge Density (pH 7.0) 0.0295

GRAVY Index0.35

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index46.66

Aliphatic Index 76.50

Aromaticity 0.0833

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2532.99

LogP -27.36

H-bond Donors 99.0

H-bond Acceptors 93.0

Rotatable Bonds 208.0

Heavy Atoms 443.0

Ring Count 8.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048877 VERIFIED: YES

Provenance & Taxonomy

OrganismCrassostrea gigas [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

RECORD: Rec_0076273 VERIFIED: NO