Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC936H1419N209O285S7

DescriptionStandard

        QIDDLAEVDYSFSSSPAVFQPFIDLDLKGVFFPAGNYTDSPYVAASLTIPDQNDPMLYLAFSEYFFQTSSFAYYTAGAFTMTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPIISLQKDSFTVQIQGSVEVLAVLPDSTIQSLFTLNIVANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20383.96 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-13.24

Net Charge (pH 7.4) -13.52

Charge Density (pH 7.0) -0.0720

GRAVY Index0.31

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index44.38

Aliphatic Index 95.92

Aromaticity 0.1359

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7835.51

LogP -85.51

H-bond Donors 265.0

H-bond Acceptors 279.0

Rotatable Bonds 649.0

Heavy Atoms 1437.0

Ring Count 36.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155723 VERIFIED: NO

Provenance & Taxonomy

OrganismTychaedon coryphoeus (Karoo scrub-robin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria