Peptide Database

Peptide NameTemporin-ALa (Amolopin-2a)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC326H538N88O97S2

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDEPDERNAEVEKRFLPIVGKLLSGLSGLLGK
    

Molecular Weight7306.42 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.74

Charge Density (pH 7.0) -0.0232

GRAVY Index-0.23

Hydrophobic Moment 0.68

Boman Index-0.05

Instability Index39.50

Aliphatic Index 109.69

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3022.68

LogP -24.83

H-bond Donors 105.0

H-bond Acceptors 98.0

Rotatable Bonds 257.0

Heavy Atoms 513.0

Ring Count 6.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077840 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic

TargetEscherichia coli

RECORD: Rec_0105144 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic

TargetCandida albicans

RECORD: Rec_0334718 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Cytotoxic Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0355900 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops loloensis [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial