Peptide Database

Peptide NameHolin (Protein P35)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length117 amino acids

Chemical FormulaC582H889N147O161S8

DescriptionStandard

        MMENDEWWKYLIFPLVATLGGIVNYSKRALAMKRFSKLEFAVEAVSAAFVGLMVTLGGAAMDLSPHWLGMAAGMSGWMGADFVKAVFSQFVQSKIAPINQPGPIDSDNDKPGRTFND
    

Molecular Weight12777.69 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-1.40

Net Charge (pH 7.4) -1.69

Charge Density (pH 7.0) -0.0120

GRAVY Index0.15

Hydrophobic Moment 0.51

Boman Index0.20

Instability Index31.48

Aliphatic Index 80.94

Aromaticity 0.1197

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 24980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4863.87

LogP -39.10

H-bond Donors 165.0

H-bond Acceptors 169.0

Rotatable Bonds 414.0

Heavy Atoms 898.0

Ring Count 25.0

Amide Bonds 124.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357765 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacteria phage PRD1 [Virus]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Cytolytic Non-hemolytic