‹ ›
MYP_115723
← PREVIOUS NEXT → BACK
Basic Information
TP1[-R5,R17G]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
16 amino acids
C89H133N27O19S4
Standard
Sequence
KWCFVCYRGICYRRCG
Physicochemical Analysis
2013.44 Da
9.25
3.72
3.45
0.2323
-0.01
0.42
-0.12
13.43
42.50
0.2500
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
767.79
-4.86
34.0
27.0
62.0
139.0
5.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0242451 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained β-hairpin peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-16; 7-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii clinical isolate 100650661:1
16 μg/mL
MIC
PMID28960954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28960954/
RECORD: Rec_0256556 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained β-hairpin peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
3-16; 7-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 43300 (MRSA)
16 μg/mL
MIC
PaperStructure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1. ACS Infect Dis. 2017 Dec 8;3(12):917-926. doi: 10.1021/acsinfecdis.7b00123. PMID: 28960954. PMID28960954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28960954/
RECORD: Rec_0274389 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained β-hairpin peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-16; 7-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 700603
16 μg/mL
MIC
PMID28960954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28960954/
RECORD: Rec_0283340 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained β-hairpin peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-16; 7-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii (strain identifier incomplete in source record)
16 μg/mL
MIC
PMID28960954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28960954/
RECORD: Rec_0338976 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
disulfide-constrained β-hairpin peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-16; 7-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43300
Qualitative antimicrobial activity (exact analogue in paper)
PMID28960954 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28960954/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records · Page 4 of 5